Pregnenolone acetate (compound #43), a nonmetabolized Pregnenolone ( HY-B0151 ) analog, can promote neurite extension and induce a change in growth cone morphology in primary cultures of cerebellar granule neurons. Pregnenolone acetate, a neurosteroid, increases microtubule polymerization. Pregnenolone acetate has the potential for neurodevelopmental diseases research.
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