Zaprinast

Overview

Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase ( PDE5 ) . Zaprinast causes a significant increase in cGMP levels in myocytes. Zaprinast is a G protein-coupled receptor 35 ( GPR35 ) agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects.

Application

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Product Information

• Catalog No.: HY-B1816
• CAS No.: 37762-06-4
• Molecular Formula: C13H13N5O2
• Molecular Weight: 271.27
• Purity: 99.83%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.08 mg/mL (7.67 mM); Clear solution
• Availability: In-stock

Source

Original product source