ARP-100

Overview

ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor ( IC 50 =12 nM). ARP-100 interacts with S1＇ pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM).

Application

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Product Information

• Catalog No.: HY-103444
• CAS No.: 704888-90-4
• Molecular Formula: C17H20N2O5S
• Molecular Weight: 364.42
• Purity: 98.07%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.86 mM); Clear solution
• Availability: In-stock

Source

Original product source