Benzoylaconine

Overview

Benzoylaconine (Benzoylaconitine) is an orally active monoester alkaloid found in the traditional Chinese medicine Aconitum carmichaelii . Benzoylaconine is an ACE2 agonist ( EC 50 : 1.5 μM) with antihypertensive and anti-heart failure effects. Benzoylaconine inhibits TLR-induced MAPK and NF-κB pathways to exert anti-inflammatory effects. Benzoylaconine upregulates the protein levels of P-gp , MRP2 , and has anti-tumor effects.

Application

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Product Information

• Catalog No.: HY-N0217
• CAS No.: 466-24-0
• Molecular Formula: C32H45NO10
• Molecular Weight: 603.70
• Purity: 99.92%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 0.92 mg/mL (1.52 mM); Clear solution
• Availability: In-stock

Source

Original product source