Saikosaponin B1

Overview

Saikosaponin B1 is a bioactive constituent of Radix Bupleuri . Saikosaponin B1 is an agonist of the 5-HT 2C receptor with an EC 50 of 147.41 μM. Saikosaponin B1 inhibits the Hedgehog (Hh) signaling pathway by targeting the transmembrane protein SMO . Sailosaponin B1 can reduce liver fibrosis. Saikosaponin B1 has anti-cancer activities thus can be studies in research for cancers such as Medulloblastoma (MB).

Application

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Product Information

• Catalog No.: HY-N0247
• CAS No.: 58558-08-0
• Molecular Formula: C42H68O13
• Molecular Weight: 780.98
• Purity: 99.42%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 100 mg/mL (128.04 mM); Clear solution
• Availability: In-stock

Source

Original product source