Mollugin

Overview

Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species ( ROS ) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 ( bone morphogenetic protein 2 ) via the p38-Smad signaling pathway.

Application

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Product Information

• Catalog No.: HY-N0316
• CAS No.: 55481-88-4
• Molecular Formula: C17H16O4
• Molecular Weight: 284.31
• Purity: 99.79%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (8.79 mM); Clear solution
• Availability: In-stock

Source

Original product source