Gomisin J

Overview

Gomisin J is a Schisandra chinensis -derived lignan that can inhibit multiple targets such as eNOS , AMPK ( LKB1 , CaMKIIβ ), fetuin-A , NF-κB , Nrf2/HO-1 , and can pass through the blood-brain barrier. Gomisin J increases NO bioavailability by activating eNOS , regulates lipid metabolism by activating the AMPK pathway, inhibits fetuin-A and NF-κB to exert anti-inflammatory effects, and activates Nrf2/HO-1 to enhance antioxidant capacity. Gomisin J has the activities of anti-hypertension, regulating liver lipid metabolism, and reducing cerebral ischemia-reperfusion injury, and can be used for research on hypertension, non-alcoholic fatty liver disease, cerebral ischemia-reperfusion injury, etc.

Application

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Product Information

• Catalog No.: HY-N0385
• CAS No.: 66280-25-9
• Molecular Formula: C22H28O6
• Molecular Weight: 388.45
• Purity: 99.97%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (6.44 mM); Clear solution
• Availability: In-stock

Source

Original product source