Diosbulbin B, a diterpene lactone, is an anticancer agent. Diosbulbin B is an orally active component of Dioscorea. bulbifera L . Diosbulbin B can inhibit cell proliferation, induce G0/G1 phase arrest and apoptosis . Diosbulbin B can induce autophagy and mitochondrial dysfunction. Diosbulbin B can induce liver injury. Diosbulbin B can be used for the research of cancer , such as non-small cell lung cancer (NSCLC).
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