Silydianin

Overview

Silydianin is a flavonolignan. Silydianin can be obtained from Silybum marianum . Silydianin inhibits PTP1B with an IC 50 of 17.38 μM. Silydianin inhibits both monophenolase and diphenolase of tyrosinase significantly, with IC 50 s of 2.6 μM and 16.5 μM, respectively. Silydianin induces Apoptosis and reduces cytokines ( IL-4 and IL-5 ). Silymarin has antioxidant, cytoprotective and immunomodulatory effects. Silydianin has antitumor activity against prostate cancer . Silymarin can be used in allergic asthma research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Phosphatase | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > Tyrosinase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-N0646
• CAS No.: 29782-68-1
• Molecular Formula: C25H22O10
• Molecular Weight: 482.44
• Purity: 99.71%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (4.31 mM); Clear solution
• Availability: In-stock

Source

Original product source