Tubeimoside I is an orally active HSPD1 inhibitor. Tubeimoside I inhibits NF-κB , MAPK , as well as regulates eNOS-VEGF . Tubeimoside I induces cytoprotective Autophagy via an Akt -mediated pathway. Tubeimoside I inhibits proinflammatory cytokine ( IL-6 and IL-1β ) production. Tubeimoside I exhibits anti-inflammatory activities. Tubeimoside I promotes angiogenesis and improves sepsis symptoms. Tubeimoside I is used in the research of inflammatory diseases, various cancers, sepsis and ischemic diseases.
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