Dehydrobruceine B

Overview

Dehydrobruceine B, a quassinoid, can be isolated from Brucea javanica . Dehydrobruceine B shows a synergistic effect with Cisplatin ( HY-17394 ) to induce apoptosis via mitochondrial method. Dehydrobruceine B increases apoptosis-inducing factor (AIF) and Bax expression and suppresses Keap1-Nrf2 .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-N10313
• CAS No.: 53730-90-8
• Molecular Formula: C23H26O11
• Molecular Weight: 478.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source