Harringtonolide

Overview

Harringtonolide is a potent RACK1 inhibitor ( IC 50 =39.66 μM in A375 cells). Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1 . Harringtonolide has plant growth inhibitory, antiviral , anti-inflammatory, and antiproliferation activities.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FAK

Product Information

• Catalog No.: HY-N10335
• CAS No.: 64761-48-4
• Molecular Formula: C19H18O4
• Molecular Weight: 310.34
• Purity: 98%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 0.5 mg/mL (1.61 mM); Clear solution
• Availability: In-stock

Source

Original product source