Moracin N

Overview

Moracin N is a benzofuran compound. At low concentrations, Moracin N activates the Keap1/Nrf2 pathway, downregulates the expression of FTH1 and ACSL4 , enhances glutathione synthesis, and inhibits neuronal ferroptosis . At high concentrations, Moracin N induces ROS accumulation, activates mitochondrial apoptosis , and triggers autophagy -mediated cell death by inhibiting the AKT/mTOR pathway. Moracin N can be used in research related to non-small cell lung cancer , hepatocellular carcinoma and ischemic brain injury.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Oxidative Stress and Inflammation | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Antioxidant Agent | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > ACSL Family | Products > Signaling Pathways > Akt | Products > Signaling Pathways > mTOR | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Tyrosinase | Products > Signaling Pathways > Ferroptosis

Product Information

• Catalog No.: HY-N11849
• CAS No.: 135248-05-4
• Molecular Formula: C19H18O4
• Molecular Weight: 310.34
• Purity: 98.02%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (8.06 mM); Clear solution
• Availability: In-stock

Source

Original product source