(R)-(+)-O-Demethylbuchenavianine

Overview

(R)-(+)-O-Demethylbuchenavianine is an inhibitor for Cyclin-dependent kinases ( CDK ). (R)-(+)-O-Demethylbuchenavianine inhibits CDK1 , CDK5 , glycogen synthase kinase-3 ( GSK3 ), cdc2-like kinase ( CLK1 ) and dual specificity tyrosine-phosphorylation-regulated kinase 1A ( DYRK1A ), with IC 50 s of 1.1, 0.95, >10, >10 and >10 μM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > DYRK | Products > Signaling Pathways > GSK-3

Product Information

• Catalog No.: HY-N12625
• CAS No.: 1364123-68-1
• Molecular Formula: C21H21NO4
• Molecular Weight: 351.40
• Purity: 98.67%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source