Mycothiazole

Overview

Mycothiazole is an inhibitor for mitochondrial electron transport chain ( ETC ) complex I. Mycothiazole exhibits cytotoxicity in cancer cells Huh7 ( IC 50 is 55.8 μM), U87 and MCF7. Mycothiazole induces apoptosis in Huh7. Mycothiazole utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathway involved transcription factors ATFS-1 and HSF1 , to extend the lifespan of C. elegans .

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Others | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Mitochondrial Metabolism

Product Information

• Catalog No.: HY-N12887
• CAS No.: 114582-75-1
• Molecular Formula: C22H32N2O3S
• Molecular Weight: 404.57
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source