Chlovalicin is found in the strain of Sporothrix sp . FO-4649. In the presence of 0.2 U/mL IL-6 , Chlovalicin inhibits the growth of L6-dependent MH60 cells with lC 50 of 7.5 μM. Chlovalicin also inhibits the growth of B16 melanoma cells with lC 50 of 38 μM. Chlovalicin also displays inhibitory activity on osteoclastogenesis.
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