Zoniporide dihydrochloride (CP-597396 dihydrochloride) is a potent and selective inhibitor of highly water-soluble sodium hydrogen exchange type 1 ( NHE-1 ). Zoniporide dihydrochloride inhibits NHE1 dependent 22Na + uptake in vitro with an IC 50 of 14 nM. Zoniporide has antitumor activity.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Na+/H+ Exchanger (NHE)
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