Betavulgarin is an anticancer agent . Betavulgarin can be isolated from Sugar Beet ( Beta vulgaris ). Betavulgarin suppresses the proliferation, migration, colony formation, and mammosphere formation of breast cancer cells, and reduces the size of the CD44 + /CD24 − subpopulation and the expression of the self-renewal- related genes C-Myc , Nanog and Oct4 . Betavulgarin promotes BCSCs death through the regulation of Stat3/Sox2 signaling.
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