Clausarin

Overview

Clausarin is a selective inhibitor of P-glycoprotein (P-gp) , inhibiting P-gp-mediated drug efflux. Clausarin significantly inhibits Daunorubicin ( HY-13062A ) efflux in K562/R7 human leukemia cells overexpressing P-gp (with Cyclosporin A ( HY-B0579 ) as a positive control). Clausarin can be naturally extracted from the roots of Citrus sinensis (sweet orange) and can be used in research related to overcoming multidrug resistance (MDR) in tumors.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > P-glycoprotein

Product Information

• Catalog No.: HY-N16684
• CAS No.: 62770-67-6
• Molecular Formula: C24H28O4
• Molecular Weight: 380.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source