Onjisaponin B

Overview

Onjisaponin B is an orally active natural product derived from Polygala tenuifolia . Onjisaponin B inhibits NF-κB p65 . Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin . Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis . Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB.

Application

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Product Information

• Catalog No.: HY-N2099
• CAS No.: 35906-36-6
• Molecular Formula: C75H112O35
• Molecular Weight: 1573.67
• Purity: 99.31%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (1.59 mM); Clear solution
• Availability: In-stock

Source

Original product source