Araloside A (Chikusetsusaponin IV), triterpenoid saponins, is an orally active component of Aralia elata . Araloside A shows low-renin-inhibitory activity with an IC 50 of 77.4 μM. Araloside A can inhibit cell proliferation and induce apoptosis . Araloside A suppresses inflammatory cytokines IL-1β and IL-6 production. Araloside A can be used for the researches of cancer , inflammation and cardiovascular disease , such as renal cell carcinoma and rheumatoid arthritis.
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