Taccalonolide A

Overview

Taccalonolide A is a microtubule stabilizer, which is a steroid isolated from Tacca chantrieri , with cytotoxic and antimalarial activities. Taccalonolide A causes G 2 -M accumulation, Bcl-2 phosphorylation and initiation of apoptosis . Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC 50 of 622 nM for SK-OV-3 cells.

Application

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Product Information

• Catalog No.: HY-N2416
• CAS No.: 108885-68-3
• Molecular Formula: C36H46O14
• Molecular Weight: 702.74
• Purity: 99.29%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (3.56 mM); Clear solution
• Availability: In-stock

Source

Original product source