Oroxylin A-7-O-glucuronide

Overview

Oroxylin A -7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A ( HY-N0560 ). Oroxylin A -7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis . Oroxylin A -7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A -7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ , and inhibits NF-κB p65 nuclear translocation. Oroxylin A -7-O-glucuronide reduces cytokine ( IL-1β , IL-6 ) production. Oroxylin A -7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer ), anti-inflammatory, and hepatoprotective activities.

Application

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Product Information

• Catalog No.: HY-N2481
• CAS No.: 36948-76-2
• Molecular Formula: C22H20O11
• Molecular Weight: 460.39
• Purity: 99.83%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution
• Availability: In-stock

Source

Original product source