Eupafolin (Nepetin) (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activities. Eupafolin inhibits IL-6 , IL-8 and MCP-1 secretion with IC 50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively in ARPE-19 cells.
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