Vitexin B-1 is an inhibitor of Bcl-2 and the agonist of Caspase . Vitexin B-1 has cytotoxic effect and induces apoptosis in MCF-7, ZR-75-1, MDA-MB-231, and COC1 cells with IC 50 s of 3.2, 2.1, 1.8 and 0.39 μM, respectively.
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