Taccalonolide B is microtubule stabilizer isolated from Tacca plantaginea , with antitumor activity. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC 50 of 208 nM.
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