Dihydrorotenone

Overview

Dihydrorotenone is an insecticide and irreversible inhibitor of mitochondrial complex I . Dihydrorotenone may induce Parkinson's disease. Dihydrorotenone induces apoptosis in human plasma cells by triggering endoplasmic reticulum stress and activating the p38 signaling pathway. The oral LD 50 of dihydrorotenone in rats is approximately 2.5 g/kg. Dihydrorotenone exhibits insecticide activity and cytotoxicity to plasma cells. Dihydrorotenone can be used to establish animal models of Parkinson's disease, safety assessment of natural pesticides, and potential cancer chemoprevention studies.

Application

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Product Information

• Catalog No.: HY-N4202
• CAS No.: 6659-45-6
• Molecular Formula: C23H24O6
• Molecular Weight: 396.43
• Purity: 99.66%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (6.31 mM); Clear solution
• Availability: In-stock

Source

Original product source