Liarozole dihydrochloride

Overview

Liarozole (R75251) dihydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA) . Liarozole dihydrochloride inhibits the cytochrome P450 ( CYP26 )-dependent 4-hydroxylation of RA ( IC 50 =7 μM), resulting in increased tissue levels of RA. Liarozole dihydrochloride shows antitumoral properties.

Application

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Product Information

• Catalog No.: HY-106019C
• CAS No.: 1883548-96-6
• Molecular Formula: C17H15Cl3N4
• Molecular Weight: 381.69
• Purity: 99.04%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (5.45 mM); Clear solution
• Availability: In-stock

Source

Original product source