Lotusine

Overview

Lotusine is an orally active signaling pathway modulator and enzyme inhibitor, with an IC 50 of 30.60 μg/mL against α-amylase and an IC 50 of 36.15 μg/mL against α-glucosidase . Lotusine inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR , Akt and ERK . Lotusine induces apoptosis , triggers G 0 /G 1 cell cycle arrest and inhibits cancer cell proliferation. Lotusine reduces lipid peroxidation and increases the activities of SOD , CAT and GPx . Lotusine is applicable to researches related to non-small cell lung cancer , type 2 diabetes and autism spectrum disorder .

Application

Products | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Depression | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Type 2 Diabetes | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Amylases | Products > Signaling Pathways > Glycosidase

Product Information

• Catalog No.: HY-N4309
• CAS No.: 6871-67-6
• Molecular Formula: C19H24NO3
• Molecular Weight: 314.40
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source