Plantainoside D

Overview

Plantainoside D, a phenylethanoid glycosides, is a IKK-β inhibitor with diverse biological activities. Plantainoside D shows inhibitory activity of angiotensin-converting enzyme ( ACE ) with an IC 50 of 2.17 mM. Plantainoside D significantly reduces the release of glutamate from nerve terminals in the cerebral cortex of rats by inhibiting the voltage-dependent calcium channel ( VDCCs ) and protein kinase C ( PKC ) signaling cascade. Plantainoside D significantly alleviates cell apoptosis by inhibiting the generation of ROS and the activation of NF-κB . Plantainoside D significantly improves acute lung injury (ALI) induced by sepsis by regulating the Sirt3/NLRP3 signaling pathway. Plantainoside D can be used for the study of neuroprotection, antioxidant, anti-inflammation, antihypertension.

Application

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Product Information

• Catalog No.: HY-N5063
• CAS No.: 147331-98-4
• Molecular Formula: C29H36O16
• Molecular Weight: 640.59
• Purity: 99.15%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.08 mg/mL (3.25 mM); Clear solution
• Availability: In-stock

Source

Original product source