Gardenin B

Overview

Gardenin B is a methoxyflavone compound and an inhibitor of USP7 , ODC ( IC 50 : 6.24 μg/mL), and Cathepsin D ( IC 50 : 5.61 μg/mL). Gardenin B exhibits antioxidant and antitumor activities. Gardenin B shows IC 50 values of 8.87 and 10.59 μg/mL for DPPH and NO scavenging, respectively, and also possesses ferric ion reducing ability. Additionally, Gardenin B can inhibit tumor cell proliferation, induce cell cycle arrest and apoptosis . Gardenin B can be used in cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ornithine decarboxylase (ODC) | Products > Signaling Pathways > Cathepsin | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Free Radical Scavengers | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Deubiquitinase

Product Information

• Catalog No.: HY-N6037
• CAS No.: 2798-20-1
• Molecular Formula: C19H18O7
• Molecular Weight: 358.34
• Purity: 99.69%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 2.5 mg/mL (6.98 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source