Okadaic acid sodium

Overview

Okadaic acid sodium, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid (sodium) has a significantly higher affinity for PP2A ( IC 50 =0.1-0.3 nM), and inhibits PP1 ( IC 50 =15-50 nM), PP3 ( IC 50 =3.7-4 nM), PP4 ( IC 50 =0.1 nM), PP5 ( IC 50 =3.5 nM), but does not inhibit PP2C. Okadaic acid sodium increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid sodium induces tau phosphorylation.

Application

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Product Information

• Catalog No.: HY-N6785A
• CAS No.: 209266-80-8
• Molecular Formula: C44H67NaO13
• Molecular Weight: 826.98
• Purity: 99.98%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source