KT5720

Overview

KT5720 is a potent, cell-permeable, specific, reversible and ATP-competitive PKA inhibitor ( IC 50 =3.3 μM). KT5720 is effective in reversing MDR1-mediated multidrug resistance. KT5720 also reduces the excitability of dorsal root ganglion (DRG) neurons by attenuating Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel activity and reducing intracellular Ca2 + concentrations. KT5720 can be used in the study of haematological malignancies as well as HCN and DRG neuron-related diseases.

Application

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Product Information

• Catalog No.: HY-N6789
• CAS No.: 108068-98-0
• Molecular Formula: C32H31N3O5
• Molecular Weight: 537.61
• Purity: 98.53%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source