Isoviolanthin is a flavonoid glycoside. Isoviolanthin can be extracted from Dendrobium officinale . Isoviolanthin has a strong affinity for binding to KDM6B , CHAC2 , ESCO2 , and IPO4 . Isoviolanthin decreases MMP-2 and MMP-9 . Isoviolanthin inhibits TGF-β/Smad and PI3K/Akt/mTOR signaling pathways. Isoviolanthin increases Fhl3 expression. Isoviolanthin has cytoprotective effects. Isoviolanthin has anticancer activity against hepatocellular carcinoma.
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