Ent-(+)-Verticilide

Ent-(+)-Verticilide
  • CAS No.:2056011-05-1
  • Grade:99.91%
  • Formula:C44H76N4O12
  • M.W.:853.09

Overview

ent-(+)-verticilide is a potent and selective inhibitor of cardiac ryanodine receptor (RyR2) calcium release channels with antiarrhythmic activity. ent-(+)-verticilide inhibits RyR2-mediated diastolic Ca2+ leak and exhibits higher potency and a distinct mechanism of action compared with theDantrolene and Tetracaine. ent-(+)-verticilide is a useful tool to investigate the therapeutic potential of targeting RyR2 hyperactivity in heart and brain pathologies.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Calcium Channel

Product Information

  • Catalog No.: HY-N7491A
  • CAS No.: 2056011-05-1
  • Molecular Formula: C44H76N4O12
  • Molecular Weight: 853.09
  • Purity: 99.91%
  • Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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