Neriifolin

Overview

Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na + , K + -ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells [2 .

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Atg8/LC3 | Products > Signaling Pathways > Na+/K+ ATPase | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Beclin1

Product Information

• Catalog No.: HY-N8441
• CAS No.: 466-07-9
• Molecular Formula: C30H46O8
• Molecular Weight: 534.68
• Purity: 99.70%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.68 mM); Clear solution
• Availability: In-stock

Source

Original product source