Malabaricone C

Overview

Malabaricone C is an orally active and noncompetitive sphingomyelin synthase ( SMS ) inhibitor with IC 50 values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells.

Application

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Product Information

• Catalog No.: HY-N8518
• CAS No.: 63335-25-1
• Molecular Formula: C21H26O5
• Molecular Weight: 358.43
• Purity: 99.46%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (6.97 mM); Clear solution
• Availability: In-stock

Source

Original product source