L-Buthionine-(S,R)-sulfoximine

Overview

L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC 50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

Application

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Product Information

• Catalog No.: HY-106376A
• CAS No.: 83730-53-4
• Molecular Formula: C8H18N2O3S
• Molecular Weight: 222.31
• Purity: 99.95%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 100 mg/mL (449.82 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source