Degalactotigonin

Overview

Degalactotigonin is a saponin-selective inhibitor targeting the EGFR , GSK3β and Hedgehog/Gli1 pathways and can be isolated from Solanum nigrum ( Solanum nigrum ). Degalactotigonin inhibits EGFR phosphorylation and the downstream Akt/ERK signaling pathway, and at the same time inhibits the Hedgehog/Gli1 pathway through GSK3β inactivation, thereby inducing cancer cell apoptosis , arresting the cell cycle, and inhibiting migration and invasion. Degalactotigonin can be used in targeted research on malignant tumors such as pancreatic cancer and osteosarcoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Hedgehog | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > ERK | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Akt

Product Information

• Catalog No.: HY-N9684
• CAS No.: 39941-51-0
• Molecular Formula: C50H82O22
• Molecular Weight: 1035.17
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source