ANT308 is a vasoactive intestinal polypeptide ( VIP receptor ) antagonist. ANT308 significantly enhances the activation and proliferation of T cells. ANT308 inhibits the migration and metastasis, induces apoptosis of melanoma tumor cells by inhibiting VIP-VPAC2 signaling and reducing the expression of MCAM and N-cadherin . ANT308 can be used for the studies of acute myeloid leukemia (AML) and uveal melanoma (UVM).
Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PACAP Receptor | Products > Signaling Pathways > Apoptosis
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