S-Propargylcysteine (SPRC), a structural analog of S-allyl cysteine (SAC), is a slow H 2 S-releasing compound. S-Propargylcysteine reduces Ca 2+ accumulation and inflammatory cytokines, inhibits STAT3 , and elevates p53 and Bax . S-Propargylcysteine has anti-inflammatory activity and protects mice against acute pancreatitis. S-Propargylcysteine also has cardioprotective, neuroprotective acitivties.
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