ALRT1550 (LGD1550) is a selective retinoic acid receptor ( RAR ) agonist that binds RARs with exceptional potency, with K d values of approximately 1-4 nM. ALRT1550 exhibits anti-proliferative activity, with an IC 50 value of 0.22 nM in UMSCC-22B squamous carcinoma cells. In a mouse tumor xenograft model, ALRT1550 inhibited tumor growth in a dose-dependent manner, achieving a maximum inhibition rate of 89%. ALRT1550 is applicable for research in the field of cancer .
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