Nebentan potassium

Overview

Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ET A receptor antagonist through the modification of Bosentan ( HY-A0013 ). Nebentan potassium inhibits [ 125 I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with K i of 0.697 nM and 569 nM, respectively. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo.

Application

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Product Information

• Catalog No.: HY-106994A
• CAS No.: 342005-82-7
• Molecular Formula: C24H20KN5O5S
• Molecular Weight: 529.61
• Purity: 98.30%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 1.67 mg/mL (3.15 mM); Clear solution
• Availability: In-stock

Source

Original product source