Suberoyl bis-hydroxamic acid

Overview

Suberoyl bis-hydroxamic acid (Suberohydroxamic acid; SBHA) is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor with ID 50 values of 0.25 μM and 0.30 μM, respectively.Suberoyl bis-hydroxamic acid renders MM cells susceptible to apoptosis and facilitates the mitochondrial apoptotic pathways.Suberoyl bis-hydroxamic acid can be used for the study of medullary thyroid carcinoma (MTC).

Application

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Product Information

• Catalog No.: HY-W009776
• CAS No.: 38937-66-5
• Molecular Formula: C8H16N2O4
• Molecular Weight: 204.22
• Purity: 95.0%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (12.24 mM); Clear solution
• Availability: In-stock

Source

Original product source