AC-45594

Overview

AC-45594 (4-(Hexyloxy)phenol) is a UPR activator. AC-45594 induces endoplasmic reticulum stress, activates the unfolded protein response (UPR), and drives the transition from adaptive stress signaling to terminal stress signaling, ultimately leading to cell Apoptosis . AC-45594 activates Caspase-3 , induces PARP cleavage, and increases the protein level of DR5 . AC-45594 selectively inhibits the growth of Ewing sarcoma cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > PARP

Product Information

• Catalog No.: HY-W009929
• CAS No.: 18979-55-0
• Molecular Formula: C12H18O2
• Molecular Weight: 194.27
• Purity: 99.94%
• Storage: RT, stored under nitrogen. In solvent -80°C, 1 year , -20°C, 6 months
• Availability: In-stock

Source

Original product source