6-Aminonicotinamide

Overview

6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP + -dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor ( K i =0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin ( HY-17394 ), in killing cancer cells.

Application

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Product Information

• Catalog No.: HY-W010342
• CAS No.: 329-89-5
• Molecular Formula: C6H7N3O
• Molecular Weight: 137.14
• Purity: 99.95%
• Storage: 4°C, protect from light * In solvent : -80°C, 2 years; -20°C, 1 year (protect from light)
• Solubility: ≥ 2.5 mg/mL (18.23 mM); Clear solution
• Availability: In-stock

Source

Original product source