2,5-Dimethylcelecoxib

Overview

2,5-Dimethylcelecoxib is an analogue of celecoxib ( HY-14398 ) with anticancer activity but without COX-2 inhibitory activity. 2,5-Dimethylcelecoxib exerts its anti-cancer cell proliferation effect by inhibiting the core mechanism of the Wnt/β-catenin signaling pathway. 2,5-Dimethylcelecoxib also inhibits T-cell factor-dependent transcriptional activity and inhibits expression of the Wnt/β-catenin target gene products cyclin D1 and survivin .

Application

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Product Information

• Catalog No.: HY-W010995
• CAS No.: 457639-26-8
• Molecular Formula: C18H16F3N3O2S
• Molecular Weight: 395.40
• Purity: 99.57%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source