GPNA hydrochloride

Overview

GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase ( GGT ). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na + -dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na + -independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > ASCT

Product Information

• Catalog No.: HY-W011391
• CAS No.: 67953-08-6
• Molecular Formula: C11H14ClN3O5
• Molecular Weight: 303.70
• Purity: 99.72%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (6.85 mM); Clear solution
• Availability: In-stock

Source

Original product source