N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor ( NK-1R ), disrupting the binding of substance P (SP) to NK-1R . This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c ( Cytochrome c ), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1 . N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases.
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