KG-655

Overview

KG-655 is a ligand that specifically binds to the ARNT PAS-B domain. KG-655 binds to the internal cavity of ARNT PAS-B to restrict its variable folded conformation, disrupts the interaction between ARNT PAS-B and the transcriptional coactivator TACC3 , and promotes the homodimerization of ARNT PAS-B. KG-655 is widely applicable to cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FGFR

Product Information

• Catalog No.: HY-W012248
• CAS No.: 349-58-6
• Molecular Formula: C8H4F6O
• Molecular Weight: 230.11
• Purity: 99.06%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 5 mg/mL (21.73 mM); Clear solution
• Availability: In-stock

Source

Original product source